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Product Description

Micro-spin column packed with media

  • Significantly reduce time and expense of SPE (e.g., can top-load samples and centrifuge)
  • Accomodates wide spectrum of volumes and allows precise control over rates of binding and elution.
  • No filters, glues, polymers, or matrices: reducing sample loss and contamination risk

TopTip enables high-fidelity chromatographic separation of even ultra-low concentration samples.

The fine 1-2 µm slit at the bottom of the TopTip permits liquid to pass through (with pressure via centrifuge or syringe), but retains chromatographicmedia in the tip. This eliminates the need for a filter – reducing dead volume, loss of sample and contamination risk.

TopTip technology has powered research resulting in many publications: Explore literature featuring TopTip.


How TopTip works




Sold in packs of 96, except for TT3, which are sold in packs of 20.


  Volume (µL) Binding capacity Media amount
TT1 1-10 400 µg 4 mg
TT2 10-200 1000 µg 10 mg
TT3 100-1000 5000 µg 50 mg


Selected applications


Ordering information




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