TopTip

Product Description

Micro-spin column packed with media

Significantly reduce time and expense of SPE (e.g., can top-load samples and centrifuge)
Accomodates wide spectrum of volumes and allows precise control over rates of binding and elution
No filters, glues, polymers, or matrices: reducing sample loss and contamination risk

TopTip enables high-fidelity chromatographic separation of even ultra-low concentration samples.

The fine 1-2 µm slit at the bottom of the TopTip permits liquid to pass through (with pressure via centrifuge or syringe), but retains chromatographicmedia in the tip. This eliminates the need for a filter – reducing dead volume, loss of sample and contamination risk.

TopTip technology has powered research resulting in many publications: Explore literature featuring TopTip .

How TopTip works

Specifications

Sold in packs of 96, except for TT3, which are sold in packs of 20.

	Volume (µL)	Binding capacity	Media amount
TT1	1-10	400 µg	4 mg
TT2	10-200	1000 µg	10 mg
TT3	100-1000	5000 µg	50 mg

Selected applications

Ordering information

	TopTip (1-10 ul)	TopTip (10-200 ul)	TopTip (100-1000 ul)	Gel-loader TopTip
	Pack of 96	Pack of 96	Pack of 20	Pack of 96
Chromatographic Media
Silica	TT1SIO / $181.00	TT2SIO / $218.00	TT3SIO / $118.00	GT1SIO / $361.00
C-18	TT1C18 / $145.00	TT2C18 / $175.00	TT3C18 / $95.00	GT2C18 / $289.00
C-08	TT1C08 / $145.00	TT2C08 / $175.00	TT3C08 / $95.00	GT2C08 / $289.00
C-04	TT1C04 / $145.00	TT2C04 / $175.00	TT3C04 / $95.00	GT2C04 / $289.00
CN	TT1CN / $206.00	TT2CN / $281.00	TT3CN / $156.00	GT2CN / $361.00
NH2	TT1NH2 / $206.00	TT2NH2 / $281.00	TT3NH2 / $156.00	GT2NH2 / $361.00
Carbon (Hypercarb)	TT1CAR / $243.00	TT2CAR / $331.00	TT3CAR / $206.00	GT2CAR / $361.00
C18 + Carbon (Hypercarb)	TT1MC18 / $243.00	TT2MC18 / $331.00	TT3MC18 / $206.00	GT2MC18 / $361.00
Cellulose	TT1CEL / $206.00	TT2CEL / $281.00	TT3CEL / $156.00	GT2CEL / $361.00
Zirconium dioxide	TT1ZRO / $243.00	TT2ZRO / $331.00	TT3ZRO / $206.00	GT2ZRO / $361.00
ZrO2+Hypercarb	TT1ZROC / $243.00	TT2ZROC / $331.00	TT3ZROC / $206.00	GT2ZROC / $361.00
ZrO2+Poros	TT1ZROP / $243.00	TT2ZROP / $331.00	TT3ZROP / $206.00	GT2ZROP / $361.00
ZrO2+Poros+Hypercarb	TT1ZROPC / $243.00	TT2ZROPC / $331.00	TT3ZROPC / $206.00	GT2ZROPC / $361.00
Titanium dioxide	TT1TIO / $243.00	TT2TIO / $331.00	TT3TIO / $206.00	GT2TIO / $361.00
TiO2+Hypercarb	TT1TIOC / $243.00	TT2TIOC / $331.00	TT3TIOC / $206.00	GT2TIOC / $361.00
TiO2+Poros	TT1TIOP / $243.00	TT2TIOP / $331.00	TT3TIOP / $206.00	GT2TIOP / $361.00
TiO2+Poros+Hypercarb	TT1TIOPC / $243.00	TT2TIOPC / $331.00	TT3TIOPC / $206.00	GT2TIOPC / $361.00
NEW ZrO2 + TiO2	TT1TIZR / $243.00	TT2TIZR / $331.00	TT3TIZR / $206.00	GT2TIZR / $361.00
POROS RP-1	TT1PR1 / $243.00	TT2PR1 / $331.00	TT3PR1 / $181.00	GT2PR1 / $361.00
POROS RP-2	TT1PR2 / $243.00	TT2PR2 / $331.00	TT3PR2 / $181.00	GT2PR2 / $361.00
POROS weak anion exchanger	TT1PWA / $243.00	TT2PWA / $331.00	TT3PWA / $206.00	GT2PWA / $361.00
POROS strong anion exchanger	TT1PSA / $243.00	TT2PSA / $331.00	TT3PSA / $206.00	GT2PSA / $361.00
POROS strong cation exchanger	TT1PSC / $243.00	TT2PSC / $331.00	TT3PSC / $206.00	GT2PSC / $361.00
HILIC	TT1HIL / $206.00	TT2HIL / $281.00	TT3HIL / $156.00	GT2HIL / $361.00
PolyHYDROXYETHYL A	TT1PHIL / $206.00	TT2PHIL / $281.00	TT3PHIL / $156.00	GT2PHIL / $361.00
PolySULFOETHYL A (silica SCX)	TT1SSA / $206.00	TT2SSA / $281.00	TT3SSA / $156.00	GT2SSA / $361.00
PolyCAT A (silica WCX)	TT1CAT / $206.00	TT2CAT / $281.00	TT3CAT / $156.00	GT2CAT / $361.00
SilIca strong Anion (SAX)	TT1SAX / $206.00	TT2SAX / $281.00	TT3SAX / $156.00	GT2SAX / $361.00
PolyWAX LP (silica weak anion)	TT1WAX / $206.00	TT2WAX / $281.00	TT3WAX / $156.00	GT2WAX / $361.00
SDS-Removal	TT1SDS / $206.00	TT2SDS / $281.00	TT3SDS / $156.00	GT2SDS / $361.00
Affinity Media
Silica IMAC	TT1SIMAC / $243.00	TT2SIMAC / $331.00	Not Available	GT2SIMAC / $361.00
POROS IMAC	TT1IMAC / $243.00	TT2IMAC / $331.00	Not Available	GT2IMAC / $361.00
Ni	TT1NIA / $243.00	TT2NIA / $331.00	Not Available	GT2NIA / $361.00
Fe	TT1FEA / $243.00	TT2FEA / $331.00	Not Available	GT2FEA / $361.00
Ga	TT1GAA / $243.00	TT2GAA / $331.00	Not Available	GT2GAA / $361.00
Ca	TT1CAA / $243.00	TT2CAA / $331.00	Not Available	GT2CAA / $361.00
Protein A	TT1PRA / $281.00	TT2PRA / $368.00	Not Available	GT2PRA / $361.00
Protein G	TT1PRG / $318.00	TT2PRG / $493.00	Not Available	GT2PRG / $361.00
Lectin: ConA	TT1CONA / $318.00	TT2CONA / $443.00	Not Available	GT2CONA / $361.00
Lectin: WGA	TT1WGA / $443.00	TT2WGA / $568.00	Not Available	GT2WGA / $361.00
Borate	TT1BOR / $306.00	TT2BOR / $456.00	Not Available	GT2BOR / $361.00
Blue Dye	TT1BLU / $206.00	TT2BLU / $281.00	TT3BLU / $281.00	GT2BLU / $361.00
Red Dye	TT1RED / $206.00	TT2RED / $281.00	TT3RED / $281.00	GT2RED / $361.00
Immobilized Enzymes
Trypsin	TT1TRY / $331.00	TT2TRY / $456.00	Not Available	GT2TRY / $361.00
Trypsin +C-18	Not Available	Not Available	Not Available	Not Available
Trypsin+Carbon	Not Available	Not Available	Not Available	Not Available
Trypsin (poroszyme)	TT1PRZ / $556.00	TT2PRZ / $731.00	Not Available	GT2PRZ / $361.00
Sialidase	TT1SIA / $443.00	TT2SIA / $693.00	Not Available	Not Available
Trypsin adsorbed on C18	Not Available	Not Available	Not Available	Not Available
Trypsin adsorbed on HILIC	Not Available	Not Available	Not Available	Not Available
G-10	TT1G10 / $118.00	TT2G10 / $118.00	TT3G10 / $118.00	Not Available
G-25	TT1G25 / $118.00	TT2G25 / $118.00	TT3G25 / $118.00	Not Available
G-50	TT1G50 / $118.00	TT2G50 / $118.00	TT3G50 / $118.00	Not Available
G-100	TT1G100 / $118.00	TT2G100 / $118.00	TT3G100 / $118.00	Not Available
P-2	TT1P2 / $118.00	TT2P2 / $118.00	TT3P2 / $118.00	Not Available
P-4	TT1P4 / $118.00	TT2P4 / $118.00	TT3P4 / $118.00	Not Available
P-6	TT1P6 / $118.00	TT2P6 / $118.00	TT3P6 / $118.00	Not Available
Empty Tip	TT1EMT / $145.00	TT2EMT / $175.00	TT3EMT / $95.00	GT2EMT / $289.00