Micro-spin column packed with media

• Significantly reduce time and expense of SPE (e.g., can top-load samples and centrifuge)
• Accomodates wide spectrum of volumes and allows precise control over rates of binding and elution.
• No filters, glues, polymers, or matrices: reducing sample loss and contamination risk

TopTip enables high-fidelity chromatographic separation of even ultra-low concentration samples.

The fine 1-2 µm slit at the bottom of the TopTip permits liquid to pass through (with pressure via centrifuge or syringe), but retains chromatographicmedia in the tip. This eliminates the need for a filter – reducing dead volume, loss of sample and contamination risk.

TopTip technology has powered research resulting in many publications: Explore literature featuring TopTip.

How TopTip works

Specifications

Sold in packs of 96, except for TT3, which are sold in packs of 20.

Selected applications

• Antibody Enrichment TopTip
• Detergent Removal TopTip
• DNA Purification TopTip
• Glycopeptide/Glycoprotein Enrichment TopTip
• Phosphopeptide Enrichment TopTip
• Protein/Peptide Desalting TopTip
• Protein/Peptide Enrichment TopTip

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