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Product Description

Micro-SPE cartridges for broad-spectrum phospholipid removal to improve small molecule bioanalysis
Mixed TiO2/ZrO2

  • Simple, fast phospholipid capture to eliminate ion-suppression in mass spectroscopy analysis
  • Proprietary TiO2+ZrO2 mixed media optimized for broad-spectrum phospholipid removal
  • Media embedded on inner wall (no glues) to eliminate contamination, back pressure, and sample loss
  • Can be combined in series with protein precipitation CrashTips for one-step sample purification

Phospholipid Removal NuTip couples metal oxide affinity chromatography (MOAC) with Glygen’s patented NuTip micro-SPE technology. This enables efficient capture of phospholipids from small molecule samples, preventing ion-suppression in mass spec analysis (which often leads to low recovery and reproducibility).

Glygen’s unique TiO2+ZrO2 mixed media (which captures a broad spectrum of phospholipids) is embedded directly in the inner surface of the tip: there are no polymers or glues. This proprietary design prevents contamination or permeability problems common in competitor tips.

Learn more about NuTip technology.

NuTip technology has powered research resulting in many publications: Explore literature featuring NuTip.

How NuTip works


Media selection
Available with TiO2+ZrO2 mixed media

Sold in packs of 96 tips.

  Volume (ul) Binding capacity Media amount
NT1 1-10 1 µg 30 µg
NT2 10-200 2.5 µg 75 µg
NT3 10-200 15 µg 400 µg


Ordering information

Part no. Price ($) Specs  
NT1TIZR 193 Size: NuTip (1-10 µL) Media: TiO2+ZrO2
NT2TIZR 231 Size: NuTip (10-200 µL) Media: TiO2+ZrO2
NT3TIZR 281 Size: NuTip (10-200 µL) LARGE Media: TiO2+ZrO2

Phospholipid Removal NuTip


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