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Product Description

Micro-spin column (no filter) for detergent removal
SDS Removal media • HILIC

  • Significantly reduce time and expense of detergent removal (e.g., can top-load samples and centrifuge)
  • Micro-spin column allows precise control over rates of binding and elution
  • No filters, glues, polymers, or matrices: reducing sample loss and contamination risk

 Detergent Removal TopTip enables easy separation of detergent in a convenient micro-spin column.

The fine slit at the bottom of the TopTip (slit width: 1-2 µm) permits liquid to pass through (with pressure via centrifuge or syringe), but retains media in the tip. This eliminates need for a filter – reducing dead volume, loss of sample and contamination risk.

Learn more about TopTip technology.

TopTip technology has powered research resulting in many publications: Explore literature featuring TopTip.

How TopTip works


Media selection

Media Use for
SDS Removal media Selective for SDS
HILIC Effective on a broad spectrum of detergents

Sold in packs of 96 tips.

  Volume (ul) Binding capacity Media amount
TT1 1-10 400 µg 4 mg
TT2 10-200 1000 µg 10 mg
TT3 100-1000 5000 µg 50 mg

Ordering information

Part No. Price ($) Specs  
TT1SDS 206 Size: TopTip (1-10 ul) Media: SDS-Removal
TT1HIL 206 Size: TopTip (1-10 ul) Media: HILIC
TT2SDS 281 Size: TopTip (10-200 ul) Media: SDS-Removal
TT2HIL 281 Size: TopTip (10-200 ul) Media: HILIC
TT3SDS 156 Size: TopTip (100-1000 ul) Media: SDS-Removal
TT3HIL 156 Size: TopTip (100-1000 ul) Media: HILIC

Detergent Removal TopTip


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